The Consortium met in Rotterdam on the 4th-5th of November 2019 at the Erasmus Medical Center for the second Intermediate Meeting. The Project one year-activities were presented and discussed. Both chemical and biological technologies were developed to boost the regenerative potential of the osteochondral scaffold. Preclinical studies underlined both criticalities and potential for the combination of these technologies, which have been discussed and will be further investigated in the planned upcoming activities to move forward to the next project phase for the selection of the most promising scaffold.